ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase
نویسندگان
چکیده
منابع مشابه
ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase
OBJECTIVE Several members of the angiopoietin-like (ANGPTL) family of proteins, including ANGPTL3 and ANGPTL8, regulate lipoprotein lipase (LPL) activity. Deficiency in either ANGPTL3 or ANGPTL8 reduces plasma triglyceride levels and increases LPL activity, whereas overexpression of either protein does the opposite. Recent studies suggest that ANGPTL8 may functionally interact with ANGPTL3 to a...
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ژورنال
عنوان ژورنال: Molecular Metabolism
سال: 2017
ISSN: 2212-8778
DOI: 10.1016/j.molmet.2017.06.014